translational means conversion of any idea, invention, innovation into the practical and in psychology there is various theories and paradigms which need to be make practical use for the benefit of the patient and even for the community

Psychology is a very delicate though fascinating topic, which is interconnected to all aspects of living.

Psychology perception and conveying pattern been changing. Innovation yes. How can there an invention be in psychology?

Psychology isn't all about patients and treatment. Psychology is entire structure of society.

The society form Individuals or the Individiduals' form the society both are the circle of the ring. One cannot be without the other.

Whether the white supremacy with cruelty or the humble attentive Worshipping are psychological factors.

Dear Kristopher ,

Translational research is a bidirectional process that involves multidisciplinary integration among basic, clinical, practice, population, and policy-based research. The goal of translational research is to speed up scientific discovery into patient and community benefit.

What is translational research?

· Translational research was designed for the medical world. It emerged in response to concern over the long time lag between scientific discoveries and changes in treatments, practices, and health policies that incorporate the new discoveries.

What are the different types of translational research?

Translational research in biomedicine is broken down into different stages, including two-stage (T1 and T2), four-stage (T1, T2, T3, and T4), and five-stage (T1, T2, T3, T4, and T5) schemes. In a two-stage model, T1 research, refers to the "bench-to-bedside" enterprise of translating knowledge from the basic sciences into the development of new treatments and T2 research refers to translating the findings from clinical trials into everyday practice.[3] In a five-stage scheme, T1 involves basic research, T2 involves pre-clinical research, T3 involves clinical research, T4 involves clinical implementation, and T5 involves implementation in the public health sphere. Waldman et al. propose a scheme going from T0 to T5. T0 is laboratory (before human) research. In T1-translation, new laboratory discoveries are first translated to human application, which includes phase I & II clinical trials. In T2-translation, candidate health applications progress through clinical development to engender the evidence base for integration into clinical practice guidelines. This includes phase III clinical trials. In T3-translation, dissemination into community practices happens. T4-translation seeks to (1) advance scientific knowledge to paradigms of disease prevention, and (2) move health practices established in T3 into population health impact. Finally, T5-translation focuses on improving the wellness of populations by reforming suboptimal social structures.[12]

Comparison to basic research or applied research[edit]

Basic research is the systematic study directed toward greater knowledge or understanding of the fundamental aspects of phenomena and is performed without thought of practical ends. It results in general knowledge and understanding of nature and its laws.[13] For instance, basic biomedical research focuses on studies of disease processes using, for example, cell cultures or animal models[8] without consideration of the potential utility of that information.

Applied research is a form of systematic inquiry involving the practical application of science. It accesses and uses the research communities' accumulated theories, knowledge, methods, and techniques, for a specific, often state, business, or client-driven purpose.[14] Translational research forms a subset of applied research. In life-sciences, this was evidenced by a citation pattern between the applied and basic sides in cancer research that appeared around 2000.[15]

Challenges and criticisms[edit]

Critics of translational medical research (to the exclusion of more basic research) point to examples of important drugs that arose from fortuitous discoveries in the course of basic research such as penicillin and benzodiazepines,[16] and the importance of basic research in improving our understanding of basic biological facts (e.g. the function and structure of DNA) that go on to transform applied medical research.[17] Examples of failed translational research in the pharmaceutical industry include the failure of anti-aβ therapeutics in Alzheimer's disease.[18] Other problems have stemmed from the widespread irreproducibility thought to exist in translational research literature.[19]

There have been no fundamental criticisms of translational research outside the biomedical field of inquiry and translational, theory-to-policy-to-practice research is an established praxis outside the life-sciences.

What are the stages of translational research?

· Translational research is broken down into different stages, including two-stage (T1 and T2), four-stage (T1, T2, T3, and T4), and five-stage (T1, T2, T3, T4, and T5) schemes.

What are some examples of failed translational research?

· Examples of failed translational research in the pharmaceutical industry include the failure of anti-aβ therapeutics in Alzheimer's disease. Other problems have stemmed from the widespread irreproducibility thought to exist in translational research literature.

Is there translational research between preclinical and clinical models?

· Translational research that is bidirectional between preclinical and clinical models can be a daunting task, as there are many domains of human life such as language and personality that are not translated readily between human and nonhuman animals.

References:

https://www.researchgate.net/publication/349742358_Translational_Research_in_Vitiligo

https://www.researchgate.net/publication/347191936_Deconstruction_and_translation_research

https://www.researchgate.net/publication/346719435_Translational_research_in_ophthalmology

https://www.researchgate.net/publication/336376148_Translational_research

https://www.researchgate.net/publication/338393343_Translational_Research_and_Applied_Psychology_in_India

https://www.researchgate.net/publication/328593626_Translational_Research

https://www.researchgate.net/publication/350589264_Translational_Research_The_Time_is_Now

https://www.sciencedirect.com/topics/psychology/translational-research

https://en.wikipedia.org/wiki/Translational_research

https://www.psychologytoday.com/us/blog/the-good-life/200905/translational-research-in-positive-psychology

https://in.sagepub.com/en-in/sas/translational-research-and-applied-psychology-in-india/book270075

https://hss.iitd.ac.in/content/translational-research-and-applied-psychology-india

best wishes

Sandeep