What are the steps and kits to be used post immunoprecipitation of protein lysate and prior to sending it for MS so that there is a clean signal?

02 June 2023 0 8K Report

I have immunoprecipitated my protein samples with a specific antibody and we then want to send it out for Mass spec analysis to understand its interactomes. However I read that the antibody, salts etc in the sample can interfere with the mass spec signal. What kits and clean up steps should I conduct on my immunoprecipitated samples to get a clean signal on MS. Thanks

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