These are:
Body Mass Index (BMI) (kg/m2):
Elongation Index at 60 Pa (EI60) (%):
Plasma Viscosity (PV) (cP):
Blood Viscosity native hematocrit, 230s-1 (BVn230s-1 ) (cP):
Blood Viscosity corrected hematocrit, 230s-1 (BVc230s-1) (cP):
Red Blood Cell Distribution Width (RDW):
Erythrocyte Aggregation at Stasis (EA0):
Erythrocyte Aggregation at 3s-1 (EA1):
Patients are males (20-35 yrs old) have active and some have inactive systemic diseases. We did the analyses but still we need the reference values of the above mentioned parameters because we didn't find yet any international parameters for healthy young males.
First: some of your parameters need explanation as to what you are seeking.
Second: Body Mass Index are you asking how to calculate it? There is no reference range. It is what the patient is. There is what is considered lean body mass and lean body BMI. There is what is considered obesity BMI.
It is serum not plasma viscosity that is measured in the US.
RDW-SD 39-46 fL [1]
RDW-CV 11.6-14.6% in adult [2]
Method for erythrocyte aggregation is needed
Blood viscosity: Reference values are dependent on many factors, including patient age, gender, sample population, and test method, and numeric test results can have different meanings in different labs.
Scand J Clin Lab Invest. 2009;69(7):777-88. doi: 10.3109/00365510903266069.
Parameterization of red blood cell elongation index--shear stress curves obtained by ektacytometry.
Baskurt OK1, Hardeman MR, Uyuklu M, Ulker P, Cengiz M, Nemeth N, Shin S, Alexy T, Meiselman HJ.
Author information
Abstract
Measurement of red blood cell (RBC) deformability by ektacytometry yields a set of elongation indexes (EI) measured at various shear stresses (SS) presented as SS-EI curves, or tabulated data. These are useful for detailed analysis, but may not be appropriate when a simple comparison of a global parameter between groups is required. Based on the characteristic shape of SS-EI curves, two approaches have been proposed to calculate the maximal RBC elongation index (EI(max)) and the shear stress required for one-half of this maximal deformation (SS(1/2)): (i) linear Lineweaver-Burke (LB) model; (ii) Streekstra-Bronkhorst (SB) model. Both approaches have specific assumptions and thus may be subject to the measurement conditions. Using RBC treated with various concentrations of glutaraldehyde (GA) and data obtained by ektacytometry, the two approaches have been compared for nine different ranges of SS between 0.6-75 Pa. Our results indicate that: (i) the sensitivity of both models can be affected by the SS range and limits employed; (ii) over the entire range of SS-data, a non-linear curve fitting approach to the LB model gave more consistent results than a linear approach; (iii) the LB method is better for detecting SS(1/2) differences between RBC treated with 0.001-0.005% glutaraldehyde (GA) and for a 40% mixture of rigid cells but is equally sensitive to SB for 10% rigid cells; and (iv) the LB and SB methods for EI(max) are equivalent for 0.001% and 0.003% GA and 40% rigid, with the SB better for 0.005% GA and the LB better for 10% rigid.
Body Mass Index (BMI) (kg/m2)= 20.0-24.9
S Viscosity (PV) (cP): 1.00-1.24 cP
Thank you Kenneth Braunstein, I added some details to the question which is related to our recent accepted paper for publication. What do you mean by SD and CV? Still I didn’t get a clear answer.
Thank you Surendra K Rajpurohit, what do you mean by the letter “S” before viscosity?
Hi Loai, perhaps i can help you. I suggest you to follow Patrizia Caprari (the most expert haemoreologist in Italy) on RG. Beside that, i can give you the following reference value.
In my personal experience (works published in Italian Language, '1980-1995, Giornale Italiano di Angiologia) with a Broofield viscosimeter:
- Blood viscosity at SR 230 sec-1: 4.0-4.5 cp (ht between 40-45%, Brookfield viscosimeter). Higher values (up to 9 cp a lower shear rates. 155, 46, 23, 11,5 sec-1).
- Plasma viscosity is less related to shear rate and range from 1,25 to 1,4 cp. Higher value (up to 3 cp) in case of mieloma
Thank you so much Dr. Roberto Flore, these values are really helpful. For the other parameters, I am trying to contact Dr. Patrizia Caprari.
Wish you all the best and much success...Keep in touch Prof. Flore
Loai Aljerf
.. The pathophysiological significance of hyperviscosity has changed during the last decades. but many researchers always find haemorhelogy very intriguing ...
I wish to suggest that you should read also "New guidelines for hemorheological laboratory techniques" Clinical Hemorheology and Microcirculation, IOS Press,2009,42 (2),pp.75-7. Thereafter "The evolution of the meaning of blood hyperviscosity in cardiovascular physiopathology: Should we reinterpret Poiseuille?" Clinical Hemorheology and Microcirculation 42 (2009) 1–6 1 by Sandro Forconi. It's free..
Best wishes
Roberto F.
Thank you Roberto Flore, I will do that and I will add the pertinent data in the next 10 days. Keep in touch