The following article which is available in my profile may help you to determine blood barrier disruption in animals. Protective effect of hydroalcoholic extract of Mimusops elengi Linn. flowers against middle cerebral artery occlusion induced brain injury in rats. P Nagakannan · B D Shivasharan · B S Thippeswamy · V P Veerapur · Punit Bansal. Journal of Ethnopharmacology