10 October 2019 3 2K Report

1. How effective do you think cancer treatment methods are? Do you think anyone is really effective in restoring cell homeostasis?

2. It is planned to make a prototype of a vaccine, whose content is a stimulus that remains encapsulated by DNA fragments to facilitate its flow in the blood, this stimulus is an oncogene that encodes a protein called Mdm2, which is important for regulation , stability and transcriptional repression of p53 protein in cells.

With this it is sought that the Mdm2 biomolecule cannot collaborate with the mutated version of p53, since Mdm2 and p53 work together to maintain stability in cell homeostasis, and cause the body to produce new p53 protein through healthy cells in a regulated manner for the regulation of cell proliferation.

[How p53 works: regulate cell division and growth, reactivate DNA repair enzymes and programming cell death (apoptosis) to tumor cells.]

a) How effective do you think this method is to eradicate cancer?

b) Do you think that it would be feasible and expensive to apply biotechnology tools for the implementation of this idea?

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