Gut microbiota play significant roles in human health. With the help of Next-gen sequencing, we know much about the compositions of bacteria in the gut but little is known about their activities. What is the default state of bacteria in the gut? Are most bacteria living in the gut at near stationary phase with basal metabolic activity? Do they become more active after a meal? Or they are always active? For example, what will a probiotic species do in the gut after they are taken by people? How many and how long will they colonize and grow in the gut?