Proton-pump inhibitors like omeprazole appear to reduce calcium absorption from calcium carbonate more than from calcium citrate, but how do they affect the absorption from dietary intake from foods like milk, cheese, spinach, etc?
A class of drugs called proton pump inhibitors (PPIs) have become the most common medication used to suppress stomach acid production in people with reflux.
PPIs are believed to affect calcium metabolism by promoting accelerated loss of calcium from the bones in addition to impairing absorption of calcium from the diet. They have also been shown to impair absorption of magnesium, another mineral important to bone mineralization. PPIs can promote "hypermotility" of the gut , you may say that they can cause diarrhea in some users. Sometimes, this diarrhea can be misdiagnosed as IBS.they can cause food intolerances.