In my opinion the variety of forms of breast cancer is determined by a variety of gene mutations and these mutations are not always the cause of carcinogenesis ..
Accordingly proteins specific to each clinical case -specific.
And given the hormonal options do not turn out to allocate reference marker. The more markers may correlate with benign tumors, infection and other factors.
The answer to your question is the early diagnosis of breast cancer. But this is still a dream.