What are the current technologies and methods used for the development of sublingual films to achieve targeted and controlled release vitamins?

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Mani Sharma

Hi !

You can use polymeric multilayer or mucoadhesive films like HPMC, chitosan, Eudragit and incorporate controlled-release matrices or nanocarriers like polymeric nanoparticles and liposomes plus permeation enhancers to tune sublingual absorption.

References in support:

https://pmc.ncbi.nlm.nih.gov/articles/PMC10747242/

Article The Potential of Films as Transmucosal Drug Delivery Systems

Article Recent progress in orodispersible films‐mediated therapeutic...

Anastasiia Maksimenko

Thank you very much for the detailed and valuable information!