What are the conditions in which researcher is unable to decide or calculate sample size for quantitative data?

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In cross-species amplification of SSR markers, can the number of alleles remain the same as in species-specific amplification?

In the context of cross-species amplification of SSR markers, is it possible for the number of alleles detected to be consistent with or equivalent to that observed in species-specific...

16 December 2023 9,336 1 View

Pyridine is use as base as well as solvent, can i replace with other solvent and base?

which is suitable for the condensation of melonic acid and aromatic aldehyde

15 July 2023 3,425 1 View

Hello, I am currently conducting research on tDNA genotyping PCR and have a specific question regarding the methodology?

Currently i am working with ABRC mutant lines of arabidopsis and during PCR for T-DNA genotyping my results are not reproduceable. Like i got bands in LB and RP and there is no band of same primer...

14 June 2023 9,847 2 View

Does SnCl2.2H2O reacting with NaOH give us SnO or SnO2?

I would like to produce both SnO, and SnO2 powders, and have a process here and resources online are conflicting about whether the end product of the reaction below is SnO or SnO2. Please...

12 June 2023 2,824 12 View

Can someone please help me to upload the DNA multistate rdf data file to Netwrok 10.2 for median joining tree construction?

I am trying to construct a Median Joining Network Tree by using a Multistate rdf file. But the software shows an error message "Sequence number 1 contains an incorrect sign. Please correct the...

09 April 2023 9,119 0 View

What is Trace value in PCA analysis using GROMACS?

Hellp all, Recently i have successfully run the GROMACS coomand for PCA analysis of protein-ligand complex. But, there are plenty of publication indicated "Trace value" in thier result. I also...

02 April 2023 10,021 0 View

How I can Justify the use of Structural equation modeling SEM in a simple model IV→DV? Instead of using linear regression?

Hi everyone, I have applied SEM to a simple model of IV→DV (Six IV's and One DV) to check the affect of various IV on Buying Intention(DV). I know SEM is used for complex behavioral models. can it...

21 February 2023 9,142 4 View

Why i am getting not promising MMGBSA result.?

Hello everyone, i hope you all are doing well, I have performed docking study with some selected molecules along with the reference inhibitor and the docking results were for selected two...

30 January 2023 7,463 1 View

What is best QMEAN score in homology modelling..?

Hello all, hope you guys are doing well, i performed a homology modelling for a protein strucutre using SWISS-MODEL server. Onces the modelling is finished the result wizard of SWISS-MODEL...

08 June 2022 8,442 0 View

How to amplify two unique alternative transcripts of single gene using one pair of primers?

In allotetraploid B.napus plant transcriptome, Based on pacBio 3rd generation sequencing, one gene has evidence of Alternative splicing (AS) in it. This gene has four exons and produces 2 distinct...

06 January 2022 8,892 4 View

Which distribution type should I use when calculating the average particle size from TEM image? and how to calculate the error ?

average particle size calculation from TEM

04 August 2024 2,921 1 View

How to calculate effect size of AMCE (Average Marginal Component Effect) in Randomized Conjoint Experiment?

I am following Hainmueller, Hopkins, and Yamamoto's (2014) paper for my randomized conjoint experimental data analysis. The link to the paper is provided below. I received a comment from the...

02 August 2024 4,406 0 View

How to conduct a sensitivity power analysis for Kendall's Tau?

Is there a straightforward way to conduct a sensitivity power analysis for a Kendall's Tau correlation? I was considering using the sensitivity setting and "Correlation: point biserial model" test...

28 July 2024 6,133 8 View

How to estimate sample size for GWAS of continuous and discrete traits? What are the pre-requisites?

Genome-wide association study (GWAS) Continuous traits: eg. Height Discrete traits: eg. Eye color

28 July 2024 286 0 View

What is the best method for removing paraffin from plant samples prepared for microtome?

...

24 July 2024 3,087 3 View

How many samples size should I select to compare both groups?

I want to study the differences between two groups: the treatment group and the comparison group. The total population consists of 60000 women in the treatment group, distributed across different...

21 July 2024 669 3 View

How to bring baseline to zero for an absorbance data for chromatogram?

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15 July 2024 5,551 6 View

How to identify a monomeric protein species of the target without running the molecular weight standard on SEC?

I was using Superose6 10/300 Gl column for purification of my target protein. the sample consists of various oligomeric state and i would like to identify the approximate elution volume where my...

15 July 2024 5,157 2 View

How to calculate Cohen's d from CI 95 and t value from a paired sample t test?

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10 July 2024 7,186 4 View

Is VSM measurment of NdFeB alloy powder sample require any spesific sample preparation ?

Is any specific sample preparation required to perform VSM measurement of NdFeB alloy powder to get a square-shaped M-H loop? Or is it mandatory to make magnetically aligned and sintered pellets...

09 July 2024 1,969 0 View

Natacha Heutte

Hello,

For an explanatory study, it is possible to quantify a sample size from a given estimation precision by relying on a confidence interval of mean.

Obasanjo Bolarinwa

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6422571/#:~:text=Based%20on%20Table%202%2C%20in,number%20of%20k%20(number%20of

That article should help you.

David L Morgan

If your sample is not representative, then you cannot generalized from it. So, you need to be very careful in stating what your exploratory goals are.