Hello Chen Mor
The normal ranges for B and T cell counts from peripheral blood will differ for different populations. It is required that laboratories all over establish reference ranges for relative and absolute lymphocyte subsets in peripheral blood samples. Many studies have shown that different populations have distinct reference ranges. This difference is attributed to genetic factors, ethnical, and environmental characteristics.
Therefore, it is recommended that each laboratory establish its own reference range. Unfortunately, few laboratories do so, thus most patients have their results compared with reference range obtained from populations that do not represent them.
Due to differences among lymphocyte subsets in the worldwide population it becomes essential to determine reference ranges in different populations to better assess and monitor patients. So, it would not be right in this case to provide the normal ranges for B and T cell counts from peripheral blood.
Best.
Dear Chen
I concur with Malcolm. Ideally you should establish a normal range for your population since the values vary between countries, racial groups and even ages. In our laboratory, we use the following normal ranges for adults
CD19 (B cells) (cells/ul) 30-450
CD3 count 670-2180
CD4 count 480-1670
CD8 count 120-830
Good luck
Siva
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