I wanna apply the direct coupling analysis method on a certain set of proteins.
Suggested reading
http://www.pnas.org/content/108/49/E1293
I need to do some GaMD simulations using Gromacs
05 June 2019 2,293 5 View
I want to generate a graph showing the relative evolutionary constraints on single positions of a certain sequence of amino-acids (protein sequence). I came across this attached figure of E.V....
04 May 2019 1,928 1 View
In the case that a female rat delivered only one or two pups, what can I do? and how can I deal with it especially that it becomes so nervous? How can I deal with a female rat immediately after...
05 June 2015 7,068 4 View
Hi everybody In the ped format for genotype, alleles of any SNP are represented by two columns (one for each allele, separated by a space). Is a column sufficient for the haplotype to...
27 February 2021 1,965 1 View
I am currently working on gene clustering based on co-expression pattern in mouse brain. The problem is I do not have some solid way to test my result. Are there any suggestions for databases...
22 February 2021 4,374 3 View
Hi Dear researchers In ensemble-based architectural design Which algorithms are more useful for classification? What is the difference between parallel and ensemble architecture? Thanks I am...
08 February 2021 2,727 5 View
Dear community, As far as I understand, negative density features point at stuff that is in the model, but not supported by experimental data. However, in many cases (e.g. attached image), when...
06 February 2021 2,847 2 View
Hi, I am working on some 16S sequencing data, and seems some of them are low quality. I am not sure how to set the trunc value in dada2. qiime dada2 denoise-paired \ --i-demultiplexed-seqs...
30 January 2021 6,213 3 View
I am trying to measure telomere length in an ant species using the TRF method, which is a Southern blot technique. Currently, I am struggling with analyzing the images and would appreciate any...
29 January 2021 604 3 View
I want to find a database(s) or a method where I can find and bulk download all the rabbit MHC genes and domain annotation. In humans using Ensembl, all MHC genes have names and domains but in...
28 January 2021 7,722 2 View
I am working on a ligand that is co-crystalized to parotein, but the ligand is missing some residues that makes it appear as if it was separated into two ligands! what I need is to connect them...
23 January 2021 3,975 7 View
bioinformatics has a big importance in human science and lots are seeking to study that field, so it attracts me to know it's relation with poultry science and how we can benefit from it in...
20 January 2021 6,963 3 View
I'm looking for a bioinformatics website to get the chromosomal location of a radish gene id list, but in one shot instead of doing it gene by gene. Is there a way to do this? Thanks
17 January 2021 8,810 3 View