The current treatment for chronic osteomyelitis can be medical therapy (antibiotics), surgery (amputation) or reconstruction. Please, see the following article with more details and a helpfull algorithm.
I also put the algorithm separately for you (source: Walter G, Kemmerer M, Kappler C, Hoffmann R. Treatment algorithms for chronic osteomyelitis. Dtsch Arztebl Int. 2012;109(14):257-64).