Dissolution study affected by various factors.
Drug Protein binding can serve as a reservoir of drug in complex form with protein. Is it work like sustained release?
11 December 2017 7,897 3 View
Therapeutic compounds with short half lives are excellent candidates for sustained release preparations. Is it true?
11 December 2017 1,671 1 View
I want to present paper in internation conference. Suggest the best international conference outside India?
10 November 2017 7,053 2 View
U.S. Food and Drug Administration said that it had approved Otsuka Pharmaceutical Co Ltd’s Abilify MyCite, the first drug with a digital ingestion tracking system to be approved in the United...
10 November 2017 4,833 0 View
From, One newspaper article and also in one magazine (http://sharonglasgow.com/2016/04/no-disease-can-exist-in-an-alkaline-environment/), It is concluded that No disease exist in alkaline state of...
10 November 2017 308 1 View
What are impacts in pharmaceutical API manufacturing industry and finished formulation?
10 November 2017 3,120 2 View
In which case, We need to develop Sustained release formulation for drugs having High Half life (24 hr)?
10 November 2017 2,751 3 View
Pradhanmanttri Jan Aushadhi Store is an ambitious program conceived and implemented by Govt. of India to provide generic medicines at affordable prices. Pradhanmanttri Jan Aushadhi Store...
10 November 2017 1,759 0 View
Today, Many company are providing online pharmacy for different category of medicine vice versa many retailers and wholesalers are opposing online pharmacy. I would like to know that under which...
10 November 2017 5,806 5 View
Scientists have raised serious concerns about the widespread use of one of the world's most common painkillers after studies showing that codeine may be unsafe, ineffective and potentially...
10 November 2017 1,889 1 View
I am experimenting with cancer and non-cancer cells in a 12-well plate for 4 days with a seeding density 1*10^4/well, however, I noticed that the control group growth rate slows down on D3. Should...
07 August 2024 2,283 2 View
I work on MCF7 cell cell for anticaner purpose and I wa to do drug preperation the drug ( secondary metabolites extracted from Aspergillus) My question which solvent is better with these secodary...
03 August 2024 4,725 2 View
Hello, if you made a transwell assay where you incubate the cells with a nanoparticle-encapsulated drug and considering that in the oposite compartment you'll have both the free and encapsulte...
03 August 2024 2,730 1 View
I am working in the filed of long acting drugs with Nano formulation. I want to study the efficacy of my formulation in 2D cell cultures while this required media change on every two days. In such...
24 July 2024 8,696 0 View
Hello, I am searching for the binding position of a drug in a ribosome, based on previous work indicating it binds there. The resolution of the ribosome-drug Cryo-EM map is around 2.5 Å. I've been...
19 July 2024 2,155 0 View
How to calculate percentage cumulative drug release when, Total volume of dissolution media = 250ml Added formulation was equivalent to 10mg of drug Sample withdrawn = 1ml each time Sink condition...
15 July 2024 4,192 1 View
Hi, In the 6 well plate, when I am seeding the cells. Do I add 1ml of complete media to one of the wells for the control at this stage or do I wait unit I am treating the plates to do that? Also...
13 July 2024 9,783 1 View
In my country, there is a lot of public outcry in relation to the presence of drug injection and related behaviors in public. Hence at least the bigger cities would probably benefit from the...
08 July 2024 8,903 1 View
Hello everyone reading this topic! It is well known that microcrystalline cellulose 102 is recommended for use in direct compression technology, however, like other grades, it has poor flowability...
08 July 2024 2,807 0 View
I used forcite module of Material Studio software to simulate the dissolution of zinc production waste in deep eutectic solvent. UFF force field has been used for the optimization of molecules,...
02 July 2024 7,494 1 View
