Were the Lewis lung carcinoma cells derived from a male or female mouse?

How to compare 2 samples recruited with different sampling methods?

If I want to compare characteristics of 2 groups of patients, one group is recruited from a random sample of the general public while another group is from a sample with a fixed gender (male to...

26 February 2021 3,526 3 View

I have a time series data of some biochemical studies ( DNA and Chromosomal damage) which I intend to use to further predict into future ?

I have a time series data of some biochemical studies ( DNA and Chromosomal damage) which I intend to use to further predict into future without necessarily conducting the assay for an extended...

23 February 2021 7,842 1 View

How to find if Qualitative and Quantitative (discrete) variables have a relation?

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18 February 2021 7,092 11 View

Which Journals would you advise to submit a Letter which briefly talks about neurosurgical treatment of neuro-oncological patient during Sars-COV-2?

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09 February 2021 717 6 View

Any reference paper with detailing on how to hybradize Q-Learning algorithm with Genetic Algorithm, especially for a variable optimization problem?

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How can I transform 50 kb plasmid into ecoli?

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22 January 2021 8,612 3 View

How can I get the chromosomal location of a list of genes?

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Which are the Non Small Cell Lung Cancer markers?

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Which substance can I use as positive standard in MTT assay on A431 cell line (human epidermoid carcinoma)?

Hi everyone, I am planning to do an MTT assay for the cytotoxicity evaluation of several plant extracts on A431 cell line (human epidermoid carcinoma). For this I need to use a positive standard....

14 December 2020 1,470 4 View

Is there any website where I can find daily COVID-19 confirmed cases and deaths according to age and sex for Sri Lanka?

I need to calculate CFR based on age group and sex. For this, I need daily COVID-19 confirmed cases and deaths according to age and sex for Sri Lanka. Where can I find this?

13 December 2020 8,287 2 View

Pawel Buczkowicz

My suggestion is to e-mail ATCC customer service and ask them if they know. I looked at some papers from 1952 and 1955 and they only mention that they were derived from a C57BL mouse in 1951 but don't give any mention of the sex.

Saravanan Ganesan

Why dont you do a karyotyping of this cell line in comparison with male and female mouse cells of the same background.. Hope it helps!

Marie Palmnas

Thank you both for your replies. I have now found, with the help of ATCC, that the cell line is derived from a male C57BL mouse. Please see p39 of the manuscript by Sugiura and Stock, (The effect of phosphoramides on the growth of a variety of mouse and rat tumors", Cancer Res, 1955; 15:38-51) for reference.

Girija Goyal

Marie, you mean the bladder or the lung carcinoma? The reference you have listed says that the bladder carcinoma was derived from the male but does not give the sex for the lung carcinoma. The references for the lung are not available online.

Kitae Ha

The cell lines has the transcripts from Y chromosome.

https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE63758