Dear all,
If I would like to study the effect of a drug on AMPA and NMDA receptors using whole-cell voltage clamp recordings to obtain spontaneous, miniature, and evoked EPSCs, can I use the same Cs-based intrapipette solution for both NMDA and AMPA recordings? (with NMDA clamped at +40 and AMPA at -70, and currents isolated using blockers).
Thank you!
Regards,
Jia Hui