Structurally they are similar and my understanding is that the OH groups are oxidized which ultimately modulates fluorescence. Both of these molecules are identical in that respect so why is DCFDA used for ROS over CMFDA.
Shafagat Mahmudova
Dear Yosep Kumka,
Look the link. May be useful.
http://www.abcam.com/dcfda-cellular-reactive-oxygen-species-detection-assay-kit-ab113851.html
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3308605/
Regards, Shafagat
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