Thank you for mentioning these two deaded but less addressed disease. Malaria has causative protozoa which has four species, some has hepatic cycle as hypnozoite some not , very complicated pathogenesis and require vigilant study on the life cycle of the pprotoza and lastly but not the least the mosquito cycle of the protozoa. M tuberculosis is unique in excreting out superoxide dismutase which by dismutation reaction with superoxide forming soluble oxygen for survival of this obligate aerobe. Superoxide formed by any inflammation in fact gives benefit to this organism. I request to go through the published papers of this researcher in this regard.

In Zambia, tuberculosis vaccine is given to neonates after birth before they are discharged from a hospital, or at first contact with the baby usually at 6 weeks when mothers go to the facilities for postnatal or within one year. The vaccination works because people who have been vaccinated against tuberculosis, rarely or never contract tuberculosis.

Regarding the malaria vaccine, it is recently introduced in some provinces in Zambia. It is too soon to talk about its efficacy. Allegedly, the vaccine for children bellow five years (under-five). Allegedly, it will last for seven months only unlike the tuberculosis vaccine that is a one off vaccine.

BCG vaccination is meant to prevent the complicated fotm of tuberculosis like meningitis etc., it cannot give total immunity against tuberculosis. The disease is much different pathogenically from other infectious diseases. The papers published by myself may please be gone through.

If we have working vaccines, then there will be no need to discuss drug supply issues.