Triple Transgenic and the modelling of Alzheimer's disease and the link with diabetes.

01 January 2013 1 449 Report

Should we really be using information gathered from the triple transgenic mouse model of dementia to inform the development of novel therapeutics for Alzheimer's disease or to study the link between diabetes and dementia?

Joseph M Fayad

yes .alzhymer associated with metabolic syndrome seems to reverse in the early phases with gastric bypass surgery , making the group different from the typical prionic model that seems to loose weight rather than gain despite adequate intake . therefore any knowledge that can help understand the subgroup will also help to devise a much more targeted disease and the response to therapy .

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