Hi, I am also working on atherosclerosis regression but pharmaceutical approach. As per my knowledge if we can transplant heart, we can transplant aortic arch too. It can give great lead of survival of animal with suppressed atheroinflammation and its aid lesion progression. However regression of plaque may not be possible because controlling inflammatory lesion progression and foam cell deposition within the lesion is still not in a control. But we can try to reverse the foam cell motility so that entrapped foam cell can emigrate from fatty plaques intima and regression can be possible.

This is only my point of view. If you have new idea regarding this you can share. Thanks for new approach.