The discussion on the role of endophytes in enhancing bioactive compound production in medicinal plants can focus on their symbiotic interactions and influence on secondary metabolite pathways. Key areas include the biotechnological potential of endophytes for scalable production through fermentation or genetic engineering, supported by omics approaches like genomics, transcriptomics, and metabolomics to elucidate their roles. Researchers can share case studies highlighting successful enhancement of pharmacologically significant compounds and discuss novel drug leads discovered through endophyte research. Challenges such as technical limitations, ethical concerns, and ecological implications can also be addressed, alongside future directions for leveraging endophytes in drug discovery and development
The role of endophytes in enhancing bioactive compound production from medicinal plants involves their symbiotic interactions that stimulate secondary metabolite pathways and their biotechnological potential for scalable production. Discussions can include successful case studies, challenges, and future directions for leveraging endophytes in drug discovery and development.
Hi Abdelhak Maghchiche, Absolutely, you’ve highlighted the critical role of endophytes in drug discovery. I too find the potential of endophytes exciting in terms of their ability to stimulate secondary metabolite pathways that might otherwise remain dormant in plants. It would be fascinating to explore how advanced omics approaches can further unravel the molecular mechanisms behind these interactions. Additionally, addressing the challenges of scalability could open up new industrial applications.
Could anybody share case studies or recent breakthroughs in endophyte-mediated bioactive compound production from plants?
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