Hello, I'll use this platform to share a problem we're having, and I'm hoping that we'll be able to come up with a solution with the information you'll provide.

When we consider our problem, we want to bind thiol active DNA with maleimide groups to the enzyme-containing magnetite powders we make, but we noticed that the positive surface charge of our structure caused an electrostatic effect. As a result, our experiments are no repeatable. To avoid this situation, what should we use as a blocking buffer?

I look forward to reading your suggestions.