Atorvastatin used to treat Atherosclerosis, seems to causes hepatoxicity upon prolonged usage. So, to inhibit such problem we have introduced an natural substances which is reported for the hepatoprotective activity. But in actual results, it causing the herb-drug interaction(HDI). Like increase Cmax etc...

So, if any would like to share their time for discussion and help me understanding what might be the cause for this HDI.