Hello everyone,
I am conducting analysis on my data and have mostly already figured it out. However, there is still one problem I haven't been able to master.
Statistical program: SPSS 29.0
Cross-over study design with NINE (9) subjects and TWO (2) treatments:
Subjects were given treatment 1 or 2 on two separate study dates. At the end of the study all subjects had received both treatments.
After administering the treatments, the patients were monitored for blood parameter changes on NINE (9) separate measuring time points.
What I aim to do, is to compare the two different treatments and have used RM analysis to do so. Initially I defined Treatment(2) and Time(9) as Within-subject-factors and have been able to gain an answer to most of my questions.
But what I haven't understood yet is how can I compare individual measured time points (for example treatment 1 blood parameter at 30 mins compared to treatment 2 blood parameter value at 30 min) between the treatments through the RM ANOVA - to my knowledge and understanding, the output does not provide this and I haven't been able to figure out how to get it out of the analysis? Or can I? Or do I have to go about it with a different analysis completely?
Thank you!
Best Regards, Isa
Hello Isa,
I suspect you could elicit specific tests (e.g., treat 1 vs. treat 2 for the respective 30-min time point) in whatever software you're using. However, you could always just run (as many as 9) dependent t-tests to do the same thing, with some appropriate adjustment for multiple tests.
The sample size (9 paired score sets) won't offer a lot of statistical power, however, unless the treatment differences are pretty strong, no matter what kind of analysis you elect to use.
Good luck with your work.
Hello Isa Hallman The attached images can help you.
Think about them.
A and B mean your two treatments.
If I follow, this EMMEANS sub-command will give you the contrast(s) you want:
/EMMEANS = TABLES(Treatment*Time) COMPARE(Treatment)
Have you considered including Order (i.e., order in which the two treatements were received) as a between-Ss factor?
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