research that can be implemented because the best research is research that can be used for the welfare of humans and the environment around us

A scale-up study starts with analysing your process. Find the subprocesses that may be limiting. In general transport processes are limiting a process (mass transfer, heat transfer, mixing...). All these are very much depending on scale, so identify those: which subprocess is likely to become limiting at increasing scale (and which subprocess becomes not-limiting at increasing scale). Can you solve the limitation or do you have to accept it? If the last, study on the small scale the consequences.

Book Lecture Notes on Scale up / Scale down