Can SC Glucagon be used to treat hypoglycaemia in a patient with recurrent insulinoma?
In the beginning when insulinoma mass is small, use of glucagon may have some benefit but creating a futile cycle is not a long-term solution.
About half of the insulinoma do have somatostatin receptors (subtype 2) and respond to its analogue, which helps with reducing hypoglycemia. Ultimately, as the insulinoma mass increases, the only practical solution is to eliminate it - which is currently done surgically.
That is unfortunate, it would seem that not all the tumor cell mass was removed...
Yes.
As Dr. Alam said, the tumour may be residual.
DDs
are multiple insulinomas, nesidioblastosis.
Please share further clinical information if available.
Chirurgical treatment may be the election for insulinoma. Laboratory for circulationg insulin must control the patient condition periodically..
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