As a mind of philosopher-research has deviations in its mode with an initial level of thinking,formulating and hypothesis.But all hypothesis are not a well defined laws.
All hypothesis will contain qualitative and quantitative limitations???
AS a mind of Scientist - we search again and again to replace and modify to use very effectively,now a days most of the signaling studies and pathology studies are conducting on animals with an ethics statement to improve the quality standard and to simplify the methods.The basical idea on deviations of technology will improve the developmental research,fundamental research and translational research.
The objective of research and the quality of interpretational skill is an effective one to develop a RE research.