Is anyone aware of any reliable and precise methods for estimates of choroidal thickness using SS-OCT given that both currently used manual (point measurements) as well as automatic algorithms(built in) have their own inherent errors in measurements?
EDI-OCT (Heidelberg Engineering) or newest xR Avanti system (Optovue) can ,easure choroid in macular and peripheral area very well. But there is no automatic choroid measurement method.. Yet...
Automatic mapping of choroidal thickness is an active area of research.
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3862153/
http://www.ncbi.nlm.nih.gov/pubmed/23367140
However, commercial OCT machines do not have an inbuilt software for this as of now.
At the last Heidelberg Symposium, they mentioned software in the works for measuring choroidal thickness. They said they were having difficulty determining the outer boundary of the choroid, since physicians have differing opinions on this. Unfortunately, we are dependant on the software of the camera manufacturers.
Hi Amy, Thanks for the update. Are you using manual measurements as of now?
Mostly I use the measure distance tool. On a rare occasion, I have had my doctor ask me to modify the segmentation lines in order to calculate the volume. You need to move Bruch's Membrane down to the base of the choroid on all acquired scans, and then move the ILM line down to Bruch's. This is quite tedious, but worth the effort because the ETDRS thickness measurements will now represent the choroid and choriocapillaris. I recommend aquiring a "FAST" scan for this, so you only have to move 25x2 segmentation lines.
I hope that helps!
We are currently using a SS-OCT( DRI-OCT1 Atlantis) which uses the built in automatic segmentation to generate the choroidal thickness measurements in ETDRS subfields. however, these might have their own inherent errors of measurements and the reliability of these segmentation algorithm cannot go unquestioned too!!
I have read other peoples work and they used OCT to measure the macular thickness
The new Swept Source OCT is a reliable way of measuring corporal thickness.
Generally the technology behind SS-OCT should yield a more accurate choroidal thickness measurement.
Both high definition SD-OCT (manual segmentation of a single scan) and SS-OCT (automated segmentation) are comparable with a minor negligible difference (the SD-OCT is being thicker by 10 - 15 microns) and interchangeable. The difference being more significant the thicker the choroid (and also decreasing accuracy of SD-OCT).
Hi Reef,
Thanks for the update. Are you aware of any papers evaluating the automatic segmentation of SS-OCT or its agreement with manual segmentation?
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