Dear all,

I am currently conducting a cross-sectional, observational, prevalence study of vascular complications (stenosis and thrombosis) after organ transplantation of which it aims to determine the prevalence of vascular complications after organ transplantation within the all transplantations and in different subgroups (underlying disease, type transplant, age) with; and different time periods:

1- total prevalence: overall prevalence over the whole study period 2000-2020

2- period prevalence: overall prevalence in 4 periods 2000-2005, 2005-2010, 2010-2015,2015-2020

Unfortunately, I do have the baseline charasterstics of only of vascular complications group (stenosis and thrombosis, n=400) including age, gender, type, size, underlying disease, anastomosis. preoperative diameter BUT NO SUCH INFORMATION FOR NON-VASCULAR GROUP (n=5000).

Therefore, I will do an analysis only within the 400 group as total vs. thrombosis vs. stenosis.

MY QUESTION:

After comparisons of 400 patients have been completed, would it be possible to perform a regression analysis of risk factors (lets say of complications, thrombosis, and stenosis)? All significant factors will be further analyzed in a multivariate analysis to determine odds ratio and 95% confidence interval for each factor.

OR should it be exclusively performed for thrombosis vs. non-thrombosis/stenosis vs. non-stenosis of which no data other number of non-complications group.

My apology for a long discussion story; I still find it a difficult concept although after reading different resources.

Thank you in advance and regards,

Bader.

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