It is well known that content of trans fatty acids (TFA) in human milk fat reflects content of those TFA in diet. There are some publications describing big differences in TFA content in mother milk, between 1 - 7% of total fatty acids. Usually it reflects content of partially hydrogenated fats in diet which is now subject of some regulations. Another source is milk fat where are "naturally" produced TFA. Let say, we would like to use human mother milk as a biomarker of TFA exposure. In this case we need to know time relationship between TFA content in diet fat and human milk fat.
So:
1.
Is there some human active physiological mechanism changing fatty acids composition in human milk, if yes, how does it change postpartum composition of milk in time?
2.
What time period of food intake is reflected in composition of milk? Is there some strong correlation?
Dear Jili
I do not understand why you write "naturally" and not naturally. TFA in bovine milk fat originate from bacterial biohydrogenation in the rumen. Also meat from ruminants contains therefore TFA. Another possible source could be the formation by intestinal bacteria in the human. Experts (if there are any) told me that this is probably a minor source.
Greetings
Hein van Valenberg
Dear Hein,
Well, I am writing about ..."source is milk fat where are "naturally" produced TFA" - I mean milk as food for mother ....(ruminant´s milk as food). Yes, I agree that TFA are minimally produced in human body. Therefore I am looking for information whether transport of dietary TFA into human milk has some regulation mechanisms (any active transport of FAs?) or it is mostly based on concentration ratio in mother´s blood plasma. And if yes, what is time relationship between dietary intake and uptake and excretion into mother milk.
Thank you for your reaction.
Jiri