QSPR and QSAR analysis in analyzing chemical structures and molecular graph unfold hidden information of the structures and pave a crucial rule to predict the properties. The ordinary techniques in calculation are so lengthy and in some case like metric dimension becomes NP-hard problem and mostly in distance base indices becomes hard calculate and analyze molecular graph structure. Can some other digital techniques and algorithmic approach may suffices to make the calculation up to the mark but in some cases it will not possible to measure with easiness. Can a standardized technique developed a remedy so as the calculation may be understood in lucid manner. It may be helpful in creating new indices and become a standard to generate a new path way to check and modify the result instantly for novel developed Indices. The generated results may helpful in a standard way and QSPR analysis become more prolific and becomes enriched in predicting the molecular graphs and drugs properties. My question here is that how it is possible to create a standardized computational technique for topological indices calculation? More precisely the topological indices are calculated and compared with standardized computational topological indices more accurate the results are. Since the standardized topological indices will implement in QSPR analysis and that develop not only more accurate and error free results but also produce reliable results with standardized computational topological indices in graph theory. What strategy is adopted to do this?