There are reports that Botulinum toxin A Injections can improve Psoriasis vulgaris and inverse psoriasis. Botulinium toxin acts by blocking the release of acetylcholine at the neuromuscular junctions. It also inhibits release of calcitonin gene related peptide (CGRP). How Botulinum toxin A can improve psoriasis? Is it due to inhibition of release of acetylcholine/CGRP or something else?

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