Can anyone tell me how to synthesize this molecule?
1-(4-amino-2,6-diphenylpyrimidin-5-yl)ethanone. Is it available in Scifinder?
Dear all, I have some compounds which good activity against some cancer cell lines (such as DU145 (Human prostate Cancer), MDA MB-231 (human breast cancer), etc. Now I want to search for the...
31 December 2018 8,092 7 View
I developed a device for cutting the TLC plates. This is my new invention and this design is registered. I wish to commercialize this product. Please let me know if it is useful for daily...
02 March 2018 7,279 15 View
Contract Research Organizations are growing very fast and drug discovery programs are exclusively using these services. However, I think that this culture is not able to produce the drug flow as...
31 December 2017 572 4 View
Rf values (TLC and HPLC) are used to identify the drug molecules. However this information can be of great value in medicinal chemistry and drug discovery. I think there's a great correction...
11 December 2017 6,720 12 View
Rapidly changing pharmaceutical R&D strategies put medicinal chemists in big trouble. Big pharmaceuticals now a days are solely depend on CRO industry for their discovery projects. In my view...
07 August 2016 5,834 4 View
06 July 2016 7,107 5 View
Dear all, I want to convert an ester to nitrile in one step. My structure contains base labile groups so I cannot use ester amine procedures. Is there any method through which I can easily convert...
31 December 2015 3,838 20 View
Reviews play a pivotal part in present day research. However, patent searching is a tedious job. I want to write a review on anti-diabetic compounds. I want to add patented anti-diabetic compounds...
04 May 2014 3,799 6 View
Reviews play a pivotal part in present day research. However, updated reviews take a lot of efforts to design. I want to write a review on anti-diabetic compounds which are currently progressing...
04 May 2014 8,705 5 View
09 October 2013 9,083 9 View
How to calculate the RMSD values for a MD simulation using MOE?
07 August 2021 0 0 View
When I tried to energy minimization my system, I got fatal error as below. Fatal error: Atomtype opls_116 not found Although I've already added this line: ; include water #include "oplsaa.ff/spc.itp" to [molecultype] directive in my topology.
16 June 2021 0 0 View
effect of double bond on the flexibility of polymers
07 April 2021 0 0 View
I am writing to request some information for making polymer color flakes. I would appreciate the help.
17 March 2021 0 0 View
I am at the beginner level in drug design and drug discovery, and I am interested to learn more about this field. Which books are highly recommended to start from and gives me all essential...
02 March 2021 8,437 2 View
The Lanthanide contraction which is the decrease in ionic radii of the elements in the lanthanide series from atomic number 57, lanthanum, to 71, lutetium, is due to poor shielding of the 4f...
01 March 2021 2,272 4 View