Reviews play a pivotal part in present day research. However, updated reviews take a lot of efforts to design. I want to write a review on anti-diabetic compounds which are currently progressing through clinical trials. How can I search the compounds in clinical trials with structures? Is there any database which collects all the updated information on clinical candidates?
Hi Omprakash Tanwar,
Please follow this link: https://clinicaltrials.gov/
I hope it will help you
Regards
Thank you very much Sir,
When I searched the word DPP-VI inhibitors I could not get relevant information. I want that I can search the ongoing status of DPP-IV inhibitors
Frustrating, isn't it? Unfortunately such is life... There is really no good publicly available database to easily do the kind of search you describe. ClinicalTrials.gov is a comprehensive database of all clinical trials going on in the US, but it takes the information as it is provided to them. In your case, some companies submit the term DPP4, some DPP-4, some DPP-IV, others Dipeptidyl peptidase-4, etc, and many will not mention the mechanism of action at all. You will have to search all these terms separately and I would look for all trials mentioning diabetes as well...
Also, this only covers the US, for Europe, see e.g. https://www.clinicaltrialsregister.eu.
A commercial database that does a pretty good job at letting you search by mechanism-of-action and many other criteria is Thomson Reuters Integrity (former Prous Integrity) database, however this is quite expensive...
Good luck!
Dear Kayser
You are right, it is frustrating, but anyway I will find a way.
Regards
Can you share the way to find the drugs under clinical trail? I want to find the drugs which inhibites alpha glucosidase (alpha glucosidase inhibitors) Omprakash Tanwar
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