Does early COVID 19 treatment matter ?

The SARS-CoV-2 virus spreading across the world has led to surges of COVID-19 illness, hospitalizations, and death. The complex and multifaceted pathophysiology of life-threatening COVID-19...

29 December 2020 7,446 4 View

Is there a paper summarising optimisation techniques and their properties such as convergence speeds ?

I am looking for a document that summarises mathematical results for optimisation techniques : steepest descent, newton and quasi-Newton, their convergence speed in different settings...

19 December 2020 2,908 8 View

Calculation the Pump power needed in a pressurized flow system?

Hi all, I am design now a liquid high pressure flow system to be used up to 50 bar, and I am having some doubts concerning how I can estimate the pump power. Besides the pressure drop in the...

15 December 2020 8,411 1 View

Design of a membrane system to remove CO2 from a flue gas current?

Hi all, I am trying to design a membrane system to remove the CO2 from a flue gas current, and I am having difficulties in finding information. Does anyone have any technical information,...

15 December 2020 3,655 2 View

What part of heart ?

Hello You can see a transversal slice of a mouse heart in microscopie with blue coloration. My question : what part of the heart is it ? how i can recognize difference between histology of...

01 December 2020 1,000 3 View

Can the potential of LIPIDMICS improve the diagnosis and understanding of metabolic changes in various neurodegenerative disease (PD, HD, AD, MS, etc?

08 November 2020 7,209 1 View

What pressures should I choose in a reheated rankine cycle?

09 October 2020 9,117 4 View

How to estimate magnetic permeability of composite materials (Fe and paramagnetic materials)?

Do works exist about magnetic permeability calculation of ferromagnetic composite materials such as SMC or mixe of iron powder and epoxy at lower density of iron than SMC?

14 September 2020 5,591 1 View

Is there an R package for the equivalent of a Mixed ANOVA in permutation ?

Hello, I know there is an R package for permutations with two independent samples...

06 August 2020 495 2 View

I want to measure cytokine levels in mouse spinal cord tissue and I can not decide which method is best, a cytokine array or ELISA?

Hi everyone. So I need to measure different cytokines in mouse spinal cord tissue and I can not decide which method is the best one, a cytokine array or ELISA. Does anyone that has experience in...

26 July 2020 1,757 2 View

Why is the efficiency of viral mRNA electroporation in PBMC low?

Hello, I have been struggling with the electroporation of PBMC with HIV-I mRNA. Although the quality of the RNA generated is good, and the handling of the cells in meticulous, the frequency of...

27 February 2021 9,233 3 View

Is anyone else having a similar situation?

I'm looking for the genetic sequence for the TAR region of HIV. If I put Transactivator Response Region, and HIV, and "genetic sequence: into a browser...is it not unreasonable to expect to be...

10 February 2021 658 5 View

Can HIV drugs will be a provisional or recurring option against COVID-19?

Can HIV drugs will be a provisional or recurring option against COVID-19?

22 December 2020 7,872 2 View

Can the formation of drugs against coronavirus also be useful against the Influenzas virus or HIV?

Can the formation of drugs against coronavirus also be useful against the Influenzas virus or HIV? This is because these viruses shared many common proteases for viral replication.

22 December 2020 6,508 6 View

Please some paper about Adaptive immunity against viral infection???

26 April 2020 1,999 10 View

Can someone send me the list of RNA dependent RNA polymerase inhibitors?

It would be very helpful if someone can send me a link or text containing the list RNA dependent RNA POLYMERASE (RdRp) inhibitors.

20 March 2020 5,707 4 View

What is the appropriate statistical treatment to be used if our study aims to identify the level of knowledge of college students with regards to HIV?

We will use a survey which contains close-ended questions.

14 March 2020 9,676 3 View

How would I determine if a protein (PD-1) is necessary for establishment of latent infection by a virus in a CD4 memory cell line?

If I were to plan an experiment to deduce whether or not PD-1 is absolutely necessary for HIV to establish latent infection in CD4 memory cells, how would I go about doing this? More...

09 March 2020 7,774 2 View

Where can I obtain a standard HIV-1 (Clade 1) strain from?

I require HIV - 1 strain to culture on PBMC cell lines, where can I obtain the standard HIV-1 strain from?

11 December 2019 2,613 2 View

Is 15 case and 15 control is enough for flow Cytometry experiments?

I have used about 9 markers to examine NK cells by flowcytometry in HIV Vs Healthy controls. Can I get how a justification on which small sample size is enough for such experiments?? Or what is...

10 November 2019 3,518 3 View