Unfortunately, I couldn't find pKa for TIPS (triisopropylsilane) does anyone know the pKa of TIPS? and how it acts as a scavenger on peptide cleavages from resin?
It is an IEEE paper in which currently i am doing my project.
16 February 2023 8,700 1 View
I have a linear octapeptide that contains Pro and Gly, I don't know if their presence as beta turn is a benefit or something that makes it more difficult to become cyclic because I already tried...
21 January 2022 1,118 3 View
Hello, I want to make a literature review depending on some keywords and year of publication. I decided to use Scopus database as a source of data, as it is the largest abstract and citation...
12 April 2020 2,829 36 View
Autism: genetic, environment or epigenetic ?
09 March 2019 8,155 14 View
I tried to input my motion data into Quake/W which is obtained from PEER database that scaled already, when I input it into the program, it becomes skipped without any notice. the analysis says...
22 May 2018 9,600 3 View
How to correlate two XRD data from synchrotron and from Cu as energy source?
04 October 2017 7,814 13 View
I need to get All direct superclasses of one class from the ontology, and I need just named classes, not those gotten from the equivalent expression with 'AllValuesFrom' restriction. I tried with...
29 September 2017 9,418 3 View
Please tell me the ingredients, their concentrations and volumes to be incorporated in the liquid culture media to detect VL in Sri Lanka using bone marrow samples
10 September 2017 8,209 5 View
My PhD thesis were in the areas of Environmental Biotechnology and Nanotechnology while my MSc thesis was in the area of Microbiology. Which are the best options, precisely areas, in which I can...
28 August 2017 6,724 3 View
Hello , I wanna get ontology classes but not in a randomly way, I'm looking for a way to get them by their hierarchical levels: I mean showing for each level of the ontology its classes; is it...
14 May 2017 8,431 4 View
We intend to study the interaction between peptides and polymer (like PP, PE and PS) through MD simulations using Martini force fields ( Martini 2 for PP and Martini 3 for PE, PS). We have...
08 August 2024 4,842 0 View
Hi, we have measured tryptic peptides using both DDA and DIA method on QExactive. In DDA replicates i saw unusual intensity drops occurring at the same sections of chromatograms in DDA replicates...
07 August 2024 3,218 4 View
Hello, I am currently analyzing some phosphoproteomics data, but I have peptides with multiple phosphorylation sites or phosphorylations together with carbamidomethylation or oxidation. How can I...
04 August 2024 8,432 3 View
Recently I'm trying to use Sep-pack C18 1 cc Vac Cartridge (Waters: SKU: WAT054955) to desalt digested peptides. However, the recovery rate is usually 40-60%. What is the normal recovery rate?
31 July 2024 6,544 11 View
So i have a few peptides (synthesized by SPPS and not cleaved from resin) and I want to add a maleimide label. We have NHS-PEG-Maleimide and from literature it is evident that the free amine group...
18 July 2024 4,075 3 View
Hello everyone! I am currently working on the expression and purification of an antimicrobial peptide that experiences reduced activity after each freeze-thaw cycle. To improve its stability, I...
10 July 2024 6,830 1 View
Recently I looked up a literature《A Glucose-6-Phosphate Isomerase Peptide Induces T and BCell-Dependent Chronic Arthritis in C57BL/10 Mice Arthritis without Reactive Oxygen Species and...
09 July 2024 6,657 0 View
I am having trouble expressing a protein and have heard that co-transforming it can improve stability and increase expression, so I am looking to try this experiment. I only need the kinase domain...
08 July 2024 2,935 5 View
I am working on my PTM project. I have some peptide. I got the result of doing MD of those peptide without PTM in different force field like Charm-GUI, Amber, Gromacs. Now I have to do MD of those...
05 July 2024 9,346 0 View
I am using a peptide and have faced challenges in preparing a transparent peptide solution. My goal is to prepare a peptide solution in MES buffer and then use the solution to immobilize the...
20 June 2024 8,622 5 View