What is the best method to select optimal cut-off.
Is there any other method.
A molecule shows the -11.6 kcal/mol and second one -8.0 kcal/mol so why molecule (A) revealed higher binding score. Please explain major factor involve in it.
21 July 2024 954 5 View
I want to download good structures of some of the bioactive compounds of fruits. From where I can download or draw the structures?
20 May 2024 6,002 2 View
I am simulating a tunnel under blast loading using conwep method in ABAQUS,I would like to know the analysis procedure and steps of analysis?
17 May 2024 9,403 1 View
I will follow the guidelines of Genewiz for sample preparation but failed Don't figured out what is the reason? Please help me if any one face same issue. I placed Custom order at genewiz and...
28 March 2024 8,441 0 View
Dear Researchers, I hope this message finds you well. I am currently engaged in a project focusing on the IEC microgrid network and its behavior under both fault and normal operating conditions....
02 March 2024 6,857 1 View
If a compound has a lot of oxygen moities in ligand, so the docking score will be increase? If it will increase then what is the reason behind it?
16 February 2024 2,160 4 View
"I recently graduated from the School of Botany at the University of Malakand, Chakdara, Pakistan, specializing in Ecology with a focus on Crop Stress Physiology. I have practical experience in...
23 January 2024 8,363 4 View
Response needed
14 January 2024 4,464 1 View
Hello Researchers I'm beginner in 3D-QSAR please enlighten about how to evaluate the 3D-QSAR model. I've read many articles in which mentioned experimental IC50 values then validated. If have no...
26 December 2023 223 2 View
We want to learn the application of data analytics in supply chain for demand prediction.
15 October 2023 8,412 3 View
I'm trying to find a DNA extraction method for fungi that does not require equipment and heating. Is there anyone who can suggest an alternative option? Thank you
08 August 2024 4,733 2 View
Just bounced on me. Before statistically analysing significant difference, shouldn't we see if data fits normal distribution first? Is 3 replicates enough to testify the hypothesis of normal...
31 July 2024 8,141 13 View
Dear researchers, Why specific capacitance is not proportional to the specific surface area? I have material A with a surface area higher than material B, but material B is showing little bit...
26 July 2024 9,156 2 View
Hi, I need to prepare a standard curve of H2O2 to evaluate the primary products of oxidation. H2O2 I have is 35%. How do I prepare a stock of H2O2 10 microlitere. If s.o has experience, I would be...
26 July 2024 3,460 2 View
Hello, colleagues! There is commenting open for new upcoming edition of USP 1033. Validation target acceptance criteria is now different from what it used to be and it doesn't include Cpm....
23 July 2024 7,292 3 View
I have been able to assign the CHARMM forcefield to my ligand i.e. acetyl coenzyme A but not the amber forcefield. I want to run amber forcefield and the parameterization of ligand is failing. I...
15 July 2024 7,323 1 View
I used MDCK cells for my plaque assay for influenza virus and seeded 950,000cells/well in 6-well two days before infection. The virus was diluted in FBS-free MEM with 0.5ug/ml TPCK-trypsin. Here...
11 July 2024 5,669 5 View
I am trying to analyze lipids in plants; specifically pollen by using Sulfo-Phospho-Vanillin (SPV) Method! Can I prepare a standard curve for this estimation using soybean, sunflower, or olive...
01 July 2024 3,267 1 View
Hi everyone! After thinking about it on my own, I'm posting a question here. Has anyone ever tried creating qPCR standard curve samples (plasmid or DNA standard) by inserting multiple target...
30 June 2024 1,569 1 View
Good morning/day/evening salaam I’d like to ask about the FRAP assay again. I have read some articles which represent the data of frap assay as mg trolox equivalent/L, mg ascorbic acid...
27 June 2024 5,239 0 View