I have a BioTek Synergy HT plate reader and I will never purchase a different brand. The optics are first class for a multipurpose machine. I am incredibly impressed by how well it works as a scanning spectrophotometer, given this is a master of all trades machine.
We switched computers, from XP to Win7 and had to reinstall software. I had the BioTek engineers on the phone while we debugged the set-up and they wrote me a patch to get around an incompatibility in our new computer. Their support staff actually understand how their products work and how they are used in the field.
I have a BioTek Synergy with modules for chemoluminiscence and DNA quantitation. Everyone finds it quite satisfactory. The tech support is very helpful. We wish that BioTek will have a version of software for Mac OS X.