I am going to put all that I know about Nicotine and its clinical medical uses with its hazards at this ResearchGate site, to guide and warn users.
Peer-review and editorial acceptance will take much time, during which many users will suffer with advancing atherosclerosis and its numerous life-threatening complications.
Manufacturers of Nicotine Transdermal Patches do disclose hypertensive effect of nicotine in their drug information pamphlets but clinicians are generally unaware of the quantum, the implications, the complications, and the benefits of this this key efffect.
I cannot keep this information to myself, ethically and morally.
Pre-print will soon follow.
Copeptin measurement are the future for this line of research.
1. Nicotine Transdermal Patch moderately elevates systemic blood pressure within 30 minutes, which effect can persist for hours, but wanes with the passage of time. Cigarette smokers / vapers (combustion versus vaporation of nicotine) exchange one cardiovascular risk for another.
Patients with hypertension and CAD or Stroke / or prone to CAD / stroke or peripheral vascular disease disease as well should avoid / restrict Nicotine / Nicotine Transdermal Patches.
This is the first caveat for use of Nicotine Transdermal patches 21 mg/24h. More on this later.
Ambulatory Blood Pressure Monitoring (ABPM) before and after Nicotine Transdermal Patches will guide clinicans over extended-therapy with Nicotine in a very wide spectrum of medical entities.
BE WARNED.
16-OCT-2023
https://orcid.org/0000-0002/6770/5916
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