Can nanoparticles access the brain after intranasal adminitration by endocytosis?

I found that functionalized nanoparticles (190 nm) can reach the brain easier than transferrin-functionalized nanoparticles (210 nm) after 30 minutes of an intranasal administration. Is it...

09 October 2018 5,719 1 View

Can I freeze at -20 C E coli suspension for posterior extraction of DNA without affect its integrity and purity?

I am using the QIAamp DNA Mini kit 250 from QiaGen for purify genomic DNA from E. coli. I have a biomass and I am looking for the best storage conditions because I am not going to perform the DNA...

06 August 2018 9,171 2 View

Can anyone identify this type of calcite crystal?

This is a SEM image taken after 7 days of carbonation of nanolime at 60-80%RH. Those crystals were found as pure calcite by XRD, which were fully oriented to {104}. Can anyone with experience on...

17 June 2018 2,446 27 View

Significant stored energy has been released means that likelihood of much larger earthquakes in the region has reduced now. " Anyone questions this??

"However, since two major earthquakes of magnitude 7 and above have occurred in a matter of 10 days in the region toward southern part of North American tectonic plate, significant stored energy...

08 September 2017 900 1 View

Any approach to accurately quantify low protein concentrations (10-500 ng/microL)?

27 October 2014 6,599 11 View

Does anyone know of research on business model innovation for mining industry towards sustainability?

I am exploring topics for my master thesis and I am very interested in business model innovation for sustainability applied to the mining sector since in countries such as Colombia, where I come...

01 February 2014 8,184 2 View

What does "MS-revised medium supplemented..." mean?

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12 September 2013 7,972 2 View

Is there a reliable/proven method for quantifying remyelination in grey matter?

Although not as highly myelinated as white matter, there is a significant amount of myelin in cortical gray matter. I'm having trouble finding a reliable method to quantify remyelination in grey...

02 March 2013 8,451 0 View

What's the poing on installing an AC/DC/AC converter to a SCIG wind turbine?

Besides for protection purposes, if you install the SCIG to the grid through a transformer, the system automatically achieves the balance between the mechanical and electromagnetic torque...

01 January 1970 8,497 6 View

Interested in connecting this with our Cellulat system?

01 January 1970 7,948 0 View

Is There Any Feasible Method To Test Fluorescent Compounds Other Than Fluorescence Spectrometers ??

Is There Any Feasible Method To Test The Efficiency Of Fluorescent Compounds Other Than UV Spectrometers ? Suggestions Would Be Appreciated !

02 March 2021 5,785 3 View

Is there a powerful system for the security of the systems distributed on IoT systems?

Is there a powerful system for the security of the systems distributed on IoT systems?

02 March 2021 3,858 10 View

How Relativistic effects is one reason for lanthanide contraction?

The Lanthanide contraction which is the decrease in ionic radii of the elements in the lanthanide series from atomic number 57, lanthanum, to 71, lutetium, is due to poor shielding of the 4f...

01 March 2021 2,272 4 View

What SPSS analysis should I run with one IV (with two levels) and two DVs?

Hi, I am trying to figure out which test would be most appropriate to run for the following question: Is there a difference in task blood pressure between smokers and non-smokers? There are two...

01 March 2021 8,235 2 View

Does anyone know HRM channel in a 2 plex QIAGEN Rotor- Gene Q qPCR can be used as a separate channel?

I am going to have 3 different probes in my qPCR work that I am going to do. But I realized that the machine we have in the lab is a Rotor-Gene Q 2plex HRM Platform, saying it has green, yellow,...

01 March 2021 8,544 1 View

Samples to study circular dichroism (chirality)?

I want to build a low-cost polarimeter to study circular dichroism (chirality). What type of samples can I use? I am looking for samples that can be found outside the laboratory.

01 March 2021 9,101 3 View

How to accurately quantify chitin?

Hi all, I have been working on the quantification of chitin in insect samples and feed for a while but I can notice that the quantification methods (e.g. exposure to HCl, NaOH, and weighing sample...

01 March 2021 1,843 2 View

Is it possible for two human neuronal cell lines to have different gene sequence for the same protein?

I am looking at the ATP1A2 (Sodium/Potassium ATPase alpha subunit 2) in two human neuronal cell lines. Expression levels of this protein seems to be almost equal when detected by one antibody....

01 March 2021 3,607 3 View

Genome-wide gene identification protocol ?

Is there any book chapter/book, webpage or research article available to understand genome-wide gene identification?

28 February 2021 8,095 1 View

For modelling epoxy-based matrices (in composites), which model in ABAQUS is the most suitable, Concrete damaged plasticity or Drucker-Prager model?

I am working on developing a micromechanical FE model for predicting kink-band formation in UD composites. To model matrix plasticity, which model, out of Concrete Damaged Plasticity and...

28 February 2021 5,415 1 View