If you have a way to predict the solubility of druglike molecules, you may wish to join the new Solubility Challenge competition: Llinas A, Avdeef A. Solubility Challenge Revisited after Ten Years, with Multi-lab Shake-Flask Data, Using Tight (SD ∼ 0.17 log) and Loose (SD ∼ 0.62 log) Test Sets. J. Chem. Inf. Model. (2019) DOI: 10.1021/acs.jcim.9b00345.

If you don't have a good training set of molecules, check out:

Avdeef A. Multi-lab Intrinsic Solubility Measurement Reproducibility in CheqSol and Shake-Flask Methods. ADMET & DMPK (2019) DOI: http://dx.doi.org/10.5599/admet.698.

Deadline for submissions is 8 Sept 2019. Show us what you've got!

-Alex Avdeef