The major principle behind mRNA based technology in vaccine design and function lies in it's use to convey specific or choice transcript, encoding one or more immunogen(s), into the host cell cytoplasm as subsequent expression here, generates translated protein(s) within the membrane, which are either secreted or intracellularly located.
This is finding use to therapeutically tackle difficukt-to deal with pathogens.
As pathogens are updating there evasive tactics within the body system to shrug-off counter immune attacks on them, it is appropriate for the scientific community to update and upgrade technology and precision tools to tame and check these pathogens.
Your views are welcome and nice, as we keep brainstorming on this sensitive issue in the Science of Infectious diseases and our deck of control and check-mate efforts, dear beloved colleagues and associates.
Thank you and pax shalom to me and to you all
Great insight. I don't think there is much information on this aspect with mRNA based vaccines.
There is also a predictable nefarious effect, that is the onset of an autoimmune cascade of events.
The mRNA will be translated in the cytoplasm of Cells it penetrates into viral proteins that can prime our immune system to make specific circulating antibodies to prevent the pathogenesis of the virus if exposed.
But this mRNA bray also be incorporated In our DNA by reverse transcription and remain as part of our genome. This would heathy Cells to make viral protein that migrate to the cell membrane. In this scenario, these cells would be recognized as foreign by our immune system and be attacked causing a new autoimmune disease. There is no way to predict over the months and years after vaccination with this viral mRNA how many cells in what organs would be endangered by making this foreign protein.
Thank you to all discussants here.
We are sharing knowledge and ideas/insights.
Warm regards all
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