The diagnosis of SARS-CoV-2 infection is made by detection by RT-PCR of viral genetic material; however, some countries (especially in the Latin American region), may be limited in the ability to carry out a certain diagnosis, as well as follow-up of cases, due to the limitation of access to reagents, which can be added to economic resources (countries dependent on crude oil prices, for example).
We know that we could be under-diagnosed?
So which do you think colleagues?
What should be the action from public health?
Do we limit testing to patients with severe or severe COVID-19?
How to establish measures to contain the infection?
In a few days Brazil will start to make Quick Tests. Then we will know the real size of this epidemic around here. It can be more than Double of cases now diagnosesd. That will also impact in quarentenized people to stay home and may decrease the rate of infection. Some sources already described more than 50% of asyntomatic cases in Italy and South Korea. I hope that we can deal with this disease better than other countries due the time we had to prepare ourselves. Lets pray!
https://www.google.com/amp/s/www.bbc.com/portuguese/amp/internacional-52020458
Under-diagnosis will definitely create a false impression of actual incidence rate. Resource poor countries are already facing this problem. But when there is actual shortage of diagnostic facilities, some proxy indicators of disease surveillance should be identified and used for planning of prevention and control strategies.
Sandro Rosa Regarding the sensitivity and specificity of the rapid tests carried out in Brazil, how much risk of false positives and negatives would we be talking about?
Shubhabrata Das Due to this in Ecuador, the decision is being made to establish a CT scan of the chest due to the lack of availability of reagents in some health institutions.
What opinion do you deserve, free access to the PCR-RT test, by private laboratories, to anyone who comes to request it? This is because many people with economic resources are taking the test, in some cases only by "referred exposure", but remain asymptomatic.
I hope these quick tests to have more false positive problems. But I could not read nothing yet about it. I am taking the zikv tests as an example. If that is true, false positive is not a big problem because the person should be put in quarentine anyway. That's just an oppinion. We should check it out but those tests were approved by Anvisa already.
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