To understand the scope of the question, suppose that there are only two particles A and B in the Universe.
If A changes its position, then B must also change, because the barycenter of the system must remain unaltered. However, if the distance between both particles are very large, when the information from the position of A reaches B some time T has passed, and meanwhile A changes again. Perhaps, the existence of a single point as barycenter instead of a fuzzy region requires an instantaneous information, which contradicts relativity theory.