Is there anybody who is working on multi-output regression based Machine Learning algorithm?

26 May 2022 0 7K Report

I have got some clue that Functional API in tensorflow may work for this case. May I expect assistance from the researchers working in this area?

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Cyclization should be performed before mutation or after mutation of a linear peptide sequence by in-silico method?

I have a doubt on in-silico modeling. I want to cyclize a linear peptide sequence by in silico. Which is more favorable method I don't understand. There is 2 pathways- 1. I can cyclize a linear...

12 June 2024 2,449 2 View

What cDNA dilution can be used for qPCR reaction?

I have obtained 100 ul of pre-amplified cDNA using the SSIV SINGLE CELL PRE-AMP KIT. Now i want to make a dilution because my samples are limited and i cannot directly use the cDNA. So what...

22 May 2024 6,017 3 View

How can I calculate average dG MM/GBSA energy from selected frames of MD trajectories?

I need to calculate dG MM/GBSA energy through the MD simulation trajectories. From RMSD values I selected last 400 frames from MD trajectories. I ran thermal_mmgbsa.py script, but it calculates dG...

22 May 2024 10,076 5 View

Is it necessary to change the medium every 24 hours after drug treatment in cell line study and provide fresh drug to the cell?

I am keeping my cell line for drug treatment and monitoring its effect at 24 hrs, 48 hrs and 72 hrs? Should I change the medium every 24 hrs and give fresh drug treatment or just leave the medium...

01 May 2024 10,011 3 View

Can anyone explain the N/P charge ratio of protein DNA complex during LLPS formation?

Protein:DNA charge ratio plays an important role in forming condensates. In most cases the N/P ratio ~1 is favored. However how this ratio depends on the concentration of the protein is not...

20 April 2024 4,753 0 View

How BLUE ECONOMY can upgrade the economic profile of the nations?

The "blue economy" refers to the sustainable use of ocean resources for economic growth, improved livelihoods, and jobs while preserving the health of ocean ecosystems. It encompasses a wide range...

19 April 2024 7,456 2 View

What could be the possible reason for this different microstructure?

I've prepared the following ceramics: Sample ID = Composition LMT = Li2Mg3TiO6 LMCT = Li2(Mg2.88Ca0.12)TiO6 LMCT-MN = Li2(Mg2.88Ca0.12)(Ti0.95(Mg1/3Nb2/3)0.05)O6 LMT-MN =...

07 April 2024 4,717 2 View

How AI can assist in the progress of Oceanography?

AI has immense potential to address various aspects of climate change by enhancing our understanding of the climate system, optimizing resource usage, and developing innovative solutions. Here are...

26 March 2024 958 1 View

How to homogenize gizzard tissue using Ultrasonic cell crusher?

I want to extract RNA from chicken gizzard tissue. But currently I don't have a homogenizer. What parameters should I use, like the power, Ton, Toff, total time etc, to effectively homogenize the...

29 February 2024 8,155 0 View

Mice Calprotectin ELISA kit (Stool)?

Have anyone tried to measure calprotectin from feces sample of mice using ELISA

03 February 2024 6,049 2 View

Why 3 replicates for most biological assays? Is it enough to examine the data fits normal distribution?

Just bounced on me. Before statistically analysing significant difference, shouldn't we see if data fits normal distribution first? Is 3 replicates enough to testify the hypothesis of normal...

31 July 2024 8,141 13 View

Can any one let me know the PDE value for Tert-Butylamine in order to control in the API?

PDE value for Tert-Butylamine

24 July 2024 1,166 0 View

Biomerieux API Campy performance?

Hello, I have a somewhat weird question: has anyone had problems with campylobacter growing in the second half of the strip GLU through ERO? Have you managed to correct it? There is some...

19 July 2024 3,094 2 View

How to dilute essential oil from plants to assess the biological activity?

I have extracted essential oil from a medicinal plant and want to make several concentrations for some biological activities (Antidiabetic assay). How can i prepare the several concentrations to...

04 July 2024 8,100 4 View

What is the effect of redshift on the evolution of an AGN?

AGN (Active Galactic Nuclei) are high energy galaxies powered by supermassive blackholes. The evolution of a galaxy is characterized by parameters such as luminosity and redshift. The redshift is...

25 June 2024 3,782 2 View

Is a PhD mandatory to become an assistant professor in India?

I would like to know whether a PhD degree is mandatory or not to become an assistant professor in India. Will it be an added advantage to improve the overall academic performance indicator (API)...

19 June 2024 9,332 1 View

How to define non-linear parameters for time history direct integration case in SAP2000 using MATLAB API functions?

I use MATLAB to define SAP Model using API function but when trying to define time history direct integration case, the non-linear parameters change from the default which affect the results and...

04 June 2024 2,369 1 View

How to communicate with BlueFors temperature controller using LabView?

New temperature controller from BlueFors uses API commands. To communicate with it, I am trying to use LabView, but I don’t have experience with HTTP. I have succeeded to get data using “get”...

01 June 2024 9,719 4 View

Are You Interested in Collaborating on Chemistry Research?

Hello ResearchGate Community, I am an MS Chemistry student with a keen interest in advancing my research skills and contributing to impactful projects. As I embark on my journey in the world of...

17 May 2024 3,213 4 View

How develop anhydrous crystalline polymorph of Pregabalin API?

I am working on Project To develop anhydrous crystalline polymorph of Pregabalin API. Standard theta value : Two –theta values are 9.55 ± 0.2 and 19.13 ± 0.2 need to be match and Melting Point...

03 May 2024 6,898 0 View