Hi all,
I'm thinking about less invasive ways to measure thyroid hormone concentration in humans. Is it reasonable to consider hair and/or urine for this purpose?
Thank you in advance!
I'm not sure if anyone has measured thyroid hormones in hair or urine - that would be interesting. However, I would consider the fact that thyroid hormones directly affect hair follicle function and urinary excretion patterns. Could make the analysis and interpretation very challenging and certainly complex. Good luck!
I have done some studies looking at T3/T4 ratios in serum by HPLC with EC detection. I feel you could use such an approach on hair after extraction and SPE and urine after spe
Dr. Hurst - just curious, what volume of serum do you use for your HPLC work?
I can look those volumes up should you wish. I may also have the HPLC and EC conditions. If you wish to contact me directly you can use [email protected]
In hair you can find only lipophilic substances as written in Gow R, Thomson S, Rieder M, Van Uum S, Koren G. An assessment of cortisol analysis in hair and its clinical applications. Forensic Sci Int 2010, 20; 196(1-3): 32-7.
Unilikely you could asses thyroid hormones in this matrix beacause they are peptide hormones.
- Badges
- Science topic
- Similar topics
- Filing