Is there any method to reduce the absorption or penetration of a drug in topical formulation since the action is sought only on the surface of the skin and not beneath the skin? Your input helps me a lot.
@Hiep Nguyen: It is for removing Keratolytic treatment to remove warts and other lesions in which the epidermis produces excess skin. It needs to soften keratin (outer layer of human skin), a major component of the skin. Since the drug is an acid if it penetrates deep into the skin it leads to severe irritation.