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Questions related from Ramkumar Ponnuraj
Hi, How can we perform cleaning validation for a multivitamin multimineral formulation. Is there any regulatory guidelines which says about cleaning validation of this formulation? If so kindly...
25 July 2018 6,512 3 View
Hi, Kindly let me know the name of the Phyto steroid responsible for Bone fracture healing and also share your input to improve the bioavailability of Cissus quadrangularis Thanks in advance
01 February 2017 3,712 2 View
Can anyone send a format for Module 3 for multivitamin and mineral product as we are adding overages and we do not possess any chemical compatibility test for vitamins....
19 October 2016 8,572 1 View
How to interpret polymorphism of a material using DSC (Differential Scanning Calorimetry)? Can anyone help in this
20 April 2016 3,485 2 View
Hi, We run Infra red for a Sample with reference to the Reference Standard of the sample. Then we found % matching between sample and standard. The results indicates the sample is matching...
31 March 2016 8,776 16 View
Hi if a drug is official in a monograph and if we are following an in house method instead of the pharmacopoeial method whether the inhouse analytical method is accepted by regulatory authority of...
03 February 2016 8,175 2 View
Hi is there any ingredient or design which can improve the magnesium absorption in the body. Generally only 50% of magnesium is absorbed into the body and remaining is excreted before it gets...
10 January 2016 2,712 8 View
When a drug is size reduced, it develops static charge on them. What exactly is the mechanism involved in this?
24 June 2015 9,385 3 View
Is there any method to reduce the absorption or penetration of a drug in topical formulation since the action is sought only on the surface of the skin and not beneath the skin? Your input helps...
12 March 2015 5,488 2 View
Can anyone explain what is the actual difference between pharma grade material and a cosmetic grade material to be utiliized in a topical product. Since both these materials can be used on skin...
09 March 2015 3,943 9 View
Dear All, We thought to prepare proliposomes to be formulated as a tablet using lecithin. Please let me know how to check whether the liposomes are produced invitro using microscopic technique /...
30 December 2014 8,283 1 View
I need BEST document regarding Factorial Design along with examples and its use. Can anyone share it?
29 December 2014 288 9 View
Does any one know how to plot Kopcha graph and identify A & B. I could not find any answer for this. Want a quick reply. Thanks in advance
16 December 2014 9,615 1 View
Dear All, Can any one share me how to find A and B in Kopcha model of dissolution. Is there any software to do it? If so how to incorporate in it and get the results? Can we get it using excel...
16 December 2014 8,018 7 View
Hi, is there any methodology to be followed for sample preperation with respect to Nanoparticles as powder for TEM analysis? Whether the entrapped drug in the Nanoparticles will be visible if we...
25 November 2014 1,104 6 View
In Ionic Gelation Method Chitosan and TPP will be used to cross link and produce nanocapsules. Drug will be entrapped in the nanocapsules. My question is whether only the drug will be present...
25 November 2014 136 2 View
Dear friends, I run a FTIR spectrum of a drug and got the spectrum. I mixed with certain excipients and again run the spectrum. The principle responses in the IR spectrum related to the drug...
20 November 2014 1,215 3 View
I planned to develop nanoparticles of a drug. The drug is available both in Crystalline and Amorphous forms. The method of preparing the nanoparticles is by dissolving the drug and gelation of...
20 November 2014 3,124 3 View
Dear All, Can anyone explain me how to perform dissolution (invitro release study) of a sustained release nanoparticles? Is it possible to use the USP Dissolution Apparatus Paddle or Basket for...
20 November 2014 2,807 12 View
I planned to develop Proliposomes and provide via oral route to improve the bio-availability of the drug which is extensively metabolized in the liver. I found certain literature stating it can...
08 November 2014 8,063 2 View
We know that there are lot of antioxidant topical creams in the market. These antioxidant help to reduce the radicals and prevents for oxidative stress and aging. But I am confused whether these...
30 October 2014 3,046 5 View
Does anyone know how to calibrate the Brookfield Viscometer? Also could you please let me know where we can get the standards for it.
30 October 2014 3,155 4 View
