What is considered a good binding affinity energy value between macromolecules?

Hi everyone, Does exist any threshold for binding affinity value between macromolecules? E.g. Any value lower than -5.0 Kcal/Mol..... How to determine that the binding affinity among different...

22 September 2020 4,329 3 View

Means and SDs for proportions - How to proceed when we need the inverse data?

Hello all, I have a tricky situation here. I need a % and SDs of drug-negative urine tests across a methamphetamine study for a meta-analysis. However, the study brings the % and SDs of...

30 March 2020 9,494 3 View

Meta-analysis - what if we have two treatment groups?

Dear all, I'm writing a meta-analysis about treatment of stimulants use disorders. I am pooling data from RCTs using a certain class of medications. However, some of the described studies used...

03 July 2019 5,014 3 View

How do I get RRRs rather than ORs from Multinomial Regression on SAS?

I have run a proc surveylogistic model using link=glogit on sas. The idea is to run a multinomial regression model. However, whenever I run the model with it covariates, SAS provides an output...

18 January 2019 8,977 6 View

What is the best way to combine/merge/concat datasets of different size?

I want to know if have some way to combine datasets with a different number of instances into one so that the final dataset is not biased to larger datasets. For instance: we have the dataset A,...

26 September 2017 9,640 4 View

Can anyone indicate me protocols, questionnaires and tree decisions regarding environmental risk assessment of microorganisms?

environmental risk assessment quantitative risk assessment microbial risk assessment ecologial risk assessment enviromental risk assessment of microorganisms

19 March 2017 2,056 3 View

How can I dissolve commercially available LDL lyophilised powder?

I have tried PBS (pH 7.4), tris-glycine buffer (7.4) and I still can't get a full dissolution of LDL.

17 January 2016 3,820 3 View

What's the current state-of-art ensemble predictors combination?

13 October 2015 1,311 3 View

Does the laser used in physical therapy entails changes in skeletal muscle in patients with cancer?

06 August 2014 7,691 3 View

Protein with very low expression. Any suggestions?

I intend to monitor post-translationally modifications on a protein with very low expression in yeast. I have already upscaled cell culture volume and done immunoprecipitation with considerable...

01 July 2014 2,105 4 View

error in running a model in Abaqus

Excessive rotation of nodes in node set ErrNodeExcessRotation-Step1

17 August 2021 0 0 View

error in modelling model in Abaqus

Excessive rotation of nodes in node set ErrNodeExcessRotation-Step1

17 August 2021 0 0 View

MGL tools

20 June 2021 0 0 View

i have some problem with chtMultiRegionSimpleFoam

--> FOAM FATAL ERROR: Maximum number of iterations exceeded From function Foam::scalar Foam::species::thermo::T(Foam::scalar, Foam::scalar, Foam::scalar, Foam::scalar (Foam::species::thermo::*)(Foam::scalar, Foam::scalar) const, Foam::scalar (Foam::species::thermo::*)(Foam::scalar, Foam::scalar) const, Foam::scalar (Foam::species::thermo::*)(Foam::scalar) const) const [with Thermo = Foam::hConstThermo >; Type = Foam::sensibleEnthalpy; Foam::scalar = double; Foam::species::thermo = Foam::species::thermo >, Foam::sensibleEnthalpy>] in file /home/ubuntu/OpenFOAM/OpenFOAM-4.1/src/thermophysicalModels/specie/lnInclude/thermoI.H at line 66. FOAM aborting #0 Foam::error::printStack(Foam::Ostream&) at ??:? #1 Foam::error::abort() at ??:? #2 Foam::heRhoThermo >, Foam::sensibleEnthalpy> > > >::calculate() at ??:? #3 Foam::heRhoThermo >, Foam::sensibleEnthalpy> > > >::correct() at ??:? #4 ? at ??:? #5 __libc_start_main in "/lib/x86_64-linux-gnu/libc.so.6" #6 ? at ??:?

24 March 2021 0 0 View

Resistor definition in Piezoelectric bimorph with ANSYS workbench

Hello, good day! I am trying to simulate similar bimorph piezoelectric harvester with below commands. However, the output power doesn't change with resistor value. Please help to find the reason. ET,10,CIRCU94,0 !SET UP RESISTOR R,1,100000 !RESISTANCE VALUE TYPE,10 !SET ELEMENT TYPE E,1,2 !CREATE RESISTOR BETWEEN NODES 1 AND 2 Thanks in advance Regards,

02 March 2021 0 0 View

Arena simulation - how do i model the following model in ARENA (see description) (new to ARENA)?

Hello, I'm fairly new to ARENA and I have the following problem: I have two queues in which, in each queue, a different order type arrives (both having an arrival rate of exponential 10). Order...

02 March 2021 2,431 3 View

How to repeat an operation on an atom selection for multiple times in PyMol?

Hi, I am trying to construct a multi-layer fibril structure from a single layer in PyMol by translating the layer along the fibril axis. For now, I am able to use the Translate command in PyMol...

02 March 2021 4,569 4 View

What is the difference between genotype and haplotype data in the ped format?

Hi everybody In the ped format for genotype, alleles of any SNP are represented by two columns (one for each allele, separated by a space). Is a column sufficient for the haplotype to...

27 February 2021 1,965 1 View

Is there an open source free software for text mining and sentiment analysis?

I am looking for a free software for text mining and sentiment analysis for my research on customer review mining (it involves calculating polarity of attributes,opinion oriented information...

25 February 2021 1,920 6 View

What software programs can directly simulate Additive Manufacturing Directed Energy Deposition (DED)?

I understand there are a lot of software programs that can simulate DED by going through specific modeling, simulation, and commands. For me, that was time consuming and results were not accurate....

24 February 2021 4,428 3 View