Why is intravenous injection a kind of systemic drug delivery (what areas cannot this injection method reach when we deliever drug/virus?

Why is intravenous injection a kind of systemic drug delivery (what areas cannot this injection method reach when we deliever drug/virus and what else other methods that could help drug/virus to...

09 October 2018 4,841 4 View

Why cannot we use prokaryotic cells (e.g. E. coli) or yeast or other low-cast cell lines to produce virus particles (e.g. rAAV or lentivirus)?

why

07 August 2018 7,082 0 View

Are there any books or references profiling morphology of various eukaryotic cells (especially mouse/human cells)?

I wish the books or references that could tell me why the morphology of these cells happen and what implications does such morphology will give us under designated conditions.

07 August 2018 4,921 0 View

Are there any websites demonstrating various biological experiments even in deepweb or darkweb (e.g. JoVE)?

experimental videos tend to be more direct sometimes.

07 August 2018 3,487 1 View

How to analyse advanced structure of a protein or protein complex in order to improve protein's some properties?

Are there any real cases in ways of bioimging or bioinformatics?

07 August 2018 5,561 0 View

Does rAAV have a potential risk to integrate a piece of DNA into host genome?

Is it true, statements below? 1. Instead, the rAAV genome is typically processed into a double-stranded circular episome through double stranded synthesis. These episomes can concatemerize,...

07 August 2018 7,208 0 View

Are there any resources introducing the interaction and mechanism of plasmid vector elements when you deliver plasmid into specific cells?

(e-)books, web, database, ......... includes prokaryotic and eukaryotic plasmid vector electments

07 August 2018 1,134 0 View

What molecular and genetic mechanism is that Lac+ E. coli shows red/pink color while Lac- E. coli shows white color on MacConkey plate?

Could you explain this from the level of Lac-associating gene and metabolic process?

05 June 2018 1,027 3 View

Are there any resources, tools, or references that can allow me to understand functions of various plasmid elements?

I know Addgene plasmid 101, only.

04 May 2018 6,418 3 View

Are there any masterpiece teaching synthetic biology especially related with plasmids construction?

Except Addgene plasmid 101

04 May 2018 1,450 3 View

error in running a model in Abaqus

Excessive rotation of nodes in node set ErrNodeExcessRotation-Step1

17 August 2021 0 0 View

error in modelling model in Abaqus

Excessive rotation of nodes in node set ErrNodeExcessRotation-Step1

17 August 2021 0 0 View

MGL tools

20 June 2021 0 0 View

i have some problem with chtMultiRegionSimpleFoam

--> FOAM FATAL ERROR: Maximum number of iterations exceeded From function Foam::scalar Foam::species::thermo::T(Foam::scalar, Foam::scalar, Foam::scalar, Foam::scalar (Foam::species::thermo::*)(Foam::scalar, Foam::scalar) const, Foam::scalar (Foam::species::thermo::*)(Foam::scalar, Foam::scalar) const, Foam::scalar (Foam::species::thermo::*)(Foam::scalar) const) const [with Thermo = Foam::hConstThermo >; Type = Foam::sensibleEnthalpy; Foam::scalar = double; Foam::species::thermo = Foam::species::thermo >, Foam::sensibleEnthalpy>] in file /home/ubuntu/OpenFOAM/OpenFOAM-4.1/src/thermophysicalModels/specie/lnInclude/thermoI.H at line 66. FOAM aborting #0 Foam::error::printStack(Foam::Ostream&) at ??:? #1 Foam::error::abort() at ??:? #2 Foam::heRhoThermo >, Foam::sensibleEnthalpy> > > >::calculate() at ??:? #3 Foam::heRhoThermo >, Foam::sensibleEnthalpy> > > >::correct() at ??:? #4 ? at ??:? #5 __libc_start_main in "/lib/x86_64-linux-gnu/libc.so.6" #6 ? at ??:?

24 March 2021 0 0 View

Resistor definition in Piezoelectric bimorph with ANSYS workbench

Hello, good day! I am trying to simulate similar bimorph piezoelectric harvester with below commands. However, the output power doesn't change with resistor value. Please help to find the reason. ET,10,CIRCU94,0 !SET UP RESISTOR R,1,100000 !RESISTANCE VALUE TYPE,10 !SET ELEMENT TYPE E,1,2 !CREATE RESISTOR BETWEEN NODES 1 AND 2 Thanks in advance Regards,

02 March 2021 0 0 View

Arena simulation - how do i model the following model in ARENA (see description) (new to ARENA)?

Hello, I'm fairly new to ARENA and I have the following problem: I have two queues in which, in each queue, a different order type arrives (both having an arrival rate of exponential 10). Order...

02 March 2021 2,431 3 View

How to repeat an operation on an atom selection for multiple times in PyMol?

Hi, I am trying to construct a multi-layer fibril structure from a single layer in PyMol by translating the layer along the fibril axis. For now, I am able to use the Translate command in PyMol...

02 March 2021 4,569 4 View

What is the difference between genotype and haplotype data in the ped format?

Hi everybody In the ped format for genotype, alleles of any SNP are represented by two columns (one for each allele, separated by a space). Is a column sufficient for the haplotype to...

27 February 2021 1,965 1 View

Is there an open source free software for text mining and sentiment analysis?

I am looking for a free software for text mining and sentiment analysis for my research on customer review mining (it involves calculating polarity of attributes,opinion oriented information...

25 February 2021 1,920 6 View

What software programs can directly simulate Additive Manufacturing Directed Energy Deposition (DED)?

I understand there are a lot of software programs that can simulate DED by going through specific modeling, simulation, and commands. For me, that was time consuming and results were not accurate....

24 February 2021 4,428 3 View